Blar i forfatter "Petersson, Jesper"

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    • Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study 

      Gallo, Valentina; Vanacore, Nicola; Bueno-de-Mesquita, H Bas; Vermeulen, Roel; Brayne, Carol; Pearce, Neil; Wark, Petra A; Ward, Heather A; Ferrari, Pietro; Jenab, Mazda; Andersen, Peter M; Wennberg, Patrik; Wareham, Nicholas; Katzke, Verena; Kaaks, Rudolf; Weiderpass, Elisabete; Peeters, Petra H; Mattiello, Amalia; Pala, Valeria; Barricante, Aurelio; Chirlaque, Maria-Dolores; Travier, Noemie; Travis, Ruth C; Sanchez, Maria-Jose; Pessah-Rasmussen, Helene; Petersson, Jesper; Tjønneland, Anne; Tumino, Rosario; Quiros, Jose Ramon; Trichopoulou, Antonia; Kyrozis, Andreas; Oikonomidou, Despoina; Masala, Giovanna; Sacerdote, Carlotta; Arriola, Larraitz; Boeing, Heiner; Vigl, Matthaeus; Claver-Chapelon, Francoise; Middleton, Lefkos; Riboli, Eilo; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-11)
      Previous case–control studies have suggested a possible increased risk of Amyotrophic Lateral Sclerosis (ALS) with physical activity (PA), but this association has never been studied in prospective cohort studies. We therefore assessed the association between PA and risk of death from ALS in the European Prospective Investigation into Cancer and Nutrition. A total of 472,100 individuals were included ...

    • Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. 

      Roaldsen, Melinda Berg; Eltoft, Agnethe; Wilsgaard, Tom; Christensen, Hanne; Engelter, Stefan T.; Indredavik, Bent; Jatužis, Dalius; Karelis, Guntis; Kõrv, Janika; Lundström, Erik; Petersson, Jesper; Putaala, Jukka; Søyland, Mary-Helen; Tveiten, Arnstein; Bivard, Andrew; Johnsen, Stein Harald; Mazya, Michael; Werring, David J; Wu, Teddy Y; de Marchis, Gian Marco; Robinson, Thompson G; Mathiesen, Ellisiv B (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-19)
      Background - Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functional ...

    • Statistical analysis plan for the randomized controlled trial Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST) 

      Eltoft, Agnethe; Wilsgaard, Tom; Roaldsen, Melinda Berg; Søyland, Mary-Helen; Lundström, Erik; Petersson, Jesper; Indredavik, Bent; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; De Marchis, Gian Marco; Werring, David J.; Robinson, Thompson; Tveiten, Arnstein; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-19)
      Background: Patients with wake-up ischemic stroke are frequently excluded from thrombolytic treatment due to unknown symptom onset time and limited availability of advanced imaging modalities. The Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST) is a randomized controlled trial of intravenous tenecteplase 0.25 mg/kg and standard care versus standard care alone (no thrombolysis) in patients ...

    • Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Eltoft, Agnethe; Jusufovic, Mirza; Søyland, Mary-Helen; Petersson, Jesper; Indredavik, Bent; Tveiten, Arnstein; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; Marco De Marchis, Gian; Wilsgaard, Tom; Werring, David; Robinson, Thompson; Mathiesen, Ellisiv B.; Berge, Eivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-14)
      <p>Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with ...